SubsidieMeestersNeuromorphic Flexible Electro/chemical Interface for in-Memory Bio-Sensing and Computing.
Develop a miniaturized, self-contained biosensing technology using neuromorphic devices for real-time monitoring and classification of neurodegenerative biomarkers in individualized healthcare.
Projectdetails
Introduction
Efficient assessment of multiple bio/chemical and electrophysiology biomarkers directly at the area of interest is an indisputable asset in individualized healthcare. However, current implantable systems and bioelectronic technologies still face limitations in ultra-sensitive bio-sensing. They address the electrical and chemical aspects fragmentally and depend on complex setups and computationally heavy off-line processing.
Limitations of Current Technologies
Conventional von Neumann architectures face limitations in efficiently handling the increasing sensor output data. This can be mainly attributed to the physical separation between sensing, memory, and computing units.
Project Objective
The overall objective is to conceptualize a first-of-its-kind, miniaturized, and self-contained biosensing technology. This technology will employ neuromorphic devices functioning as on-node sensors and processors (in-memory (bio)sensing and computing), in soft, flexible, and bio-compatible materials and format.
Demonstration and Application
I will demonstrate this technology by showcasing, in an in vivo animal model, a proof-of-concept implantable bio-interface. This interface will intelligently interrogate and classify neurodegenerative disease-related bio/chemical and electrical biomarkers. It will be coupled with active elements enabling precise adjustment of stimulation control parameters based on analog inputs.
Potential Impact
This technology holds great potential to advance our understanding and treatments of pathologies through multiplex electrical and chemical monitoring. It aims to reduce the demands for power-intensive analog-to-digital conversion and computational processing. Furthermore, it paves the way for tailored interventions, laying the foundation for next-generation biomedical modulation systems.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 1.500.000 |
| Totale projectbegroting | € 1.500.000 |
Tijdlijn
| Startdatum | 1-1-2025 |
| Einddatum | 31-12-2029 |
| Subsidiejaar | 2025 |
Partners & Locaties
Projectpartners
- UNIVERSITEIT GENTpenvoerder
- UNIVERSITA DEGLI STUDI DI PADOVA
Land(en)
Vergelijkbare projecten binnen European Research Council
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In-operando growth of organic mixed ionic-electronic conductors for brain-inspired electronics
The INFER project aims to develop brain-inspired bioelectronic devices using organic mixed ionic-electronic conductors for localized signal processing and enhanced biocompatibility.
Soft optoelectronics and ion-based circuits for diagnostics and closed-loop neuromodulation of the auditory pathway
Develop a fully implantable, biocompatible electro-optical neurostimulation system using ion gated transistors and OLEDs to enhance neural signal acquisition and treatment of sensory dysfunctions.
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Neuromorphic computing system for real-time signal monitoring and classification with ultra-low-power 2D devices
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5D Electro-Mechanical Bio-Interface for Neuronal Tissue Engineering
Develop a novel 3D biomaterial for leadless electrical and mechanical modulation to enhance brain research and neuroengineering applications.
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BioFINE aims to develop advanced flexible intraneural multielectrode arrays for improved long-term integration with peripheral nerves, enhancing bionic limb communication and neurotechnology.
Engineering Graphene for developing Neural Interfaces to revolutionize how we treat neurological diseases
INBRAIN Neuroelectronics is developing AI-powered graphene-based neural implants to enhance resolution and specificity in neuroelectronic therapies for refractory neurological disorders.
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CROSSBRAIN aims to revolutionize brain condition treatment using implantable microbots for real-time, adaptive neuromodulation and sensing in rodent models of Parkinson's Disease and Epilepsy.
In-situ & operando organiC electrochemical transistors monitored by non-destructive spectroscopies for Organic cmos-like NeuromorphIc Circuits
ICONIC aims to advance implantable AI organic electronic devices for chronic disease management by investigating PMIECs, leading to smart drug-delivery systems with enhanced accuracy and safety.