Next-gen fluorescence imaging for research and theranostics
The project aims to develop the TriScanner, a novel fluorescence microscope that enhances imaging speed, resolution, and sensitivity for multicellular systems in research and clinical applications.
Projectdetails
Introduction
Fluorescence microscopy is a key technique in the life sciences, though the method struggles to deliver fast and sensitive imaging of multicellular systems. Such samples are now becoming commonplace not only in research but also in clinical use, including spatially-resolved 'omics' and theranostics based on patient material that allow the development of personalized treatments. However, their general uptake is limited by the absence of suitable instrumentation.
Project Overview
As part of our ERC-funded research, we have invented the TriScanner, a novel fluorescence microscope that offers transformative imaging performance, including:
- Much faster imaging
- Higher resolution
- Higher sensitivity
The TriScanner is also simple, robust, and affordable. It readily addresses an urgent need in current research and healthcare, and is well-positioned to scale out from research into 'workhorse' usage in industrial R&D and diagnostics.
Development Plan
We propose to develop this idea from a concept and lab prototype into a robust demonstrator that will be showcased on a variety of highly relevant applications. Our goals include:
- Raising user awareness
- Interacting with key leaders in academia
- Collaborating with leading commercial partners
Market Exploration
This project will furthermore allow us to explore the business case and market potential, with a view to developing and selecting the optimal valorization track.
Expected Impact
We expect to deliver societal impact by providing unprecedented new imaging capabilities in a fast-moving and highly influential research field.
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 150.000 |
Totale projectbegroting | € 150.000 |
Tijdlijn
Startdatum | 1-6-2023 |
Einddatum | 30-11-2024 |
Subsidiejaar | 2023 |
Partners & Locaties
Projectpartners
- KATHOLIEKE UNIVERSITEIT LEUVENpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
Project | Regeling | Bedrag | Jaar | Actie |
---|---|---|---|---|
Low-cost, high-throughput quantitative phase microscopyThis project aims to develop a low-cost high-content screening platform using novel imaging technology to democratize access to advanced research tools in life sciences. | ERC Proof of... | € 150.000 | 2023 | Details |
A light-efficient microscope for fast volumetric imaging of photon starved samplesLowLiteScope aims to revolutionize bioluminescence microscopy by using AI-driven light field techniques for high-resolution 3D imaging of biological samples, enhancing research capabilities in life sciences. | ERC Proof of... | € 150.000 | 2024 | Details |
Fast and simple biomarker detection by computational microscopyWe developed a fast, sensitive biomarker detection method for early diagnosis and monitoring of cancer treatments, aiming to improve patient outcomes through preventative diagnostics. | ERC Proof of... | € 150.000 | 2024 | Details |
Optical Microscope for Imaging High-Speed Precision Surface ProcessesSURFLIGHT aims to revolutionize optical microscopy with a high-resolution, real-time microscope for monitoring ultrafast surface processes, enhancing catalysis R&D and reducing costs across various industries. | ERC Proof of... | € 150.000 | 2024 | Details |
Advanced X-ray Energy-sensitive Microscopy for Virtual HistologyThis project aims to develop a prototype phase-contrast micro-CT scanner for non-invasive 3D histology to enhance volumetric analysis of tissue samples, particularly lung lesions. | ERC Consolid... | € 2.000.000 | 2023 | Details |
Low-cost, high-throughput quantitative phase microscopy
This project aims to develop a low-cost high-content screening platform using novel imaging technology to democratize access to advanced research tools in life sciences.
A light-efficient microscope for fast volumetric imaging of photon starved samples
LowLiteScope aims to revolutionize bioluminescence microscopy by using AI-driven light field techniques for high-resolution 3D imaging of biological samples, enhancing research capabilities in life sciences.
Fast and simple biomarker detection by computational microscopy
We developed a fast, sensitive biomarker detection method for early diagnosis and monitoring of cancer treatments, aiming to improve patient outcomes through preventative diagnostics.
Optical Microscope for Imaging High-Speed Precision Surface Processes
SURFLIGHT aims to revolutionize optical microscopy with a high-resolution, real-time microscope for monitoring ultrafast surface processes, enhancing catalysis R&D and reducing costs across various industries.
Advanced X-ray Energy-sensitive Microscopy for Virtual Histology
This project aims to develop a prototype phase-contrast micro-CT scanner for non-invasive 3D histology to enhance volumetric analysis of tissue samples, particularly lung lesions.
Vergelijkbare projecten uit andere regelingen
Project | Regeling | Bedrag | Jaar | Actie |
---|---|---|---|---|
Revolutionizing Spatial Biology with a cutting-edge Multi-Scale Imaging platformThe NanoSCAN project aims to develop the SAFe-nSCAN platform for high-resolution 3D tissue analysis, enhancing molecular profiling and advancing personalized therapies in immuno-oncology. | EIC Transition | € 2.489.162 | 2023 | Details |
On-chip tomographic microscopy: a paraDIgm Shift for RevolUtionizing lab-on-a-chiP bioimaging technologyDISRUPT aims to revolutionize biomedical imaging with a novel lab-on-chip technology for cost-effective, high-resolution cancer detection and diagnostics using integrated tomographic microscopy and AI. | EIC Pathfinder | € 3.018.312 | 2022 | Details |
Enabling the transition to 3D digital pathology3DPATH aims to develop a clinically viable 3D tissue scanner using advanced light-sheet fluorescence microscopy to enhance histopathology accuracy and improve patient care globally. | EIC Transition | € 2.493.683 | 2025 | Details |
Photonic chip based high-throughput, multi-modal and scalable optical nanoscopy platformNanoVision aims to revolutionize optical nanoscopy with an affordable, compact, and high-throughput photonic-chip solution, enhancing accessibility and flexibility for research and clinical labs. | EIC Transition | € 2.489.571 | 2022 | Details |
Colouring the Dark in Fluorescence LightCoDaFlight aims to develop a next-generation real-time fluorescence imaging platform to enhance surgical decision-making and address unmet clinical needs through innovative technology. | EIC Pathfinder | € 2.999.300 | 2022 | Details |
Revolutionizing Spatial Biology with a cutting-edge Multi-Scale Imaging platform
The NanoSCAN project aims to develop the SAFe-nSCAN platform for high-resolution 3D tissue analysis, enhancing molecular profiling and advancing personalized therapies in immuno-oncology.
On-chip tomographic microscopy: a paraDIgm Shift for RevolUtionizing lab-on-a-chiP bioimaging technology
DISRUPT aims to revolutionize biomedical imaging with a novel lab-on-chip technology for cost-effective, high-resolution cancer detection and diagnostics using integrated tomographic microscopy and AI.
Enabling the transition to 3D digital pathology
3DPATH aims to develop a clinically viable 3D tissue scanner using advanced light-sheet fluorescence microscopy to enhance histopathology accuracy and improve patient care globally.
Photonic chip based high-throughput, multi-modal and scalable optical nanoscopy platform
NanoVision aims to revolutionize optical nanoscopy with an affordable, compact, and high-throughput photonic-chip solution, enhancing accessibility and flexibility for research and clinical labs.
Colouring the Dark in Fluorescence Light
CoDaFlight aims to develop a next-generation real-time fluorescence imaging platform to enhance surgical decision-making and address unmet clinical needs through innovative technology.