Metal-Organic-Framework Kinetic Array for Diabetes Detection

This project aims to develop a novel sensor using metal-organic frameworks to selectively detect volatile organic compounds in breath for non-invasive diabetes diagnosis.

Subsidie
€ 150.000
2024

Projectdetails

Introduction

Diabetes mellitus is a global health concern affecting 537 million people and resulting in over 6.7 million deaths yearly. Diagnosis currently relies on blood analysis, which is expensive, time-consuming, and invasive.

Alternative Diagnosis Method

Breath analysis based on the detection of volatile organic compounds (VOCs) is a promising non-invasive alternative. However, selectively measuring specific VOCs in breath is challenging due to:

  • Their low concentrations
  • The presence of interfering compounds

Need for Novel Technology

Since current miniature sensors cannot efficiently distinguish between VOCs, there is a need for a novel technology capable of distinguishing a VOC of interest from a complex background.

Project Aim

This project aims to address this challenge by combining a highly promising class of porous crystalline materials, metal-organic frameworks (MOFs), with sensor technology.

Sensing Concept

A novel sensing concept based on the kinetic selectivity in the pores of the MOFs will be leveraged to mimic nature’s approach to olfaction and enable selective sensing.

Demonstrator Development

A demonstrator will be established to enable diabetes mellitus diagnosis and prove the breakthrough potential of this disruptive sensing platform.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 150.000
Totale projectbegroting€ 150.000

Tijdlijn

Startdatum1-11-2024
Einddatum30-4-2026
Subsidiejaar2024

Partners & Locaties

Projectpartners

  • KATHOLIEKE UNIVERSITEIT LEUVENpenvoerder

Land(en)

Belgium

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