SubsidieMeesters4D Microscopy of biological materials by short pulse terahertz sources (MIMOSA)
MIMOSA aims to develop a high-resolution Tomographic Atom Probe using intense terahertz pulses for advanced biological imaging and potential commercialization.
Projectdetails
Introduction
Cryo-electron microscopy and tomography have been among the greatest achievements in biological imaging, but these techniques suffer from insufficient chemical resolution. The ultimate goal of MIMOSA is to provide an alternative to tomography at the nanoscale with a high chemical resolution for biological and medical systems, based on Tomographic Atom Probe (TAP).
Objectives
MIMOSA aims to prototype a new TAP triggered by intense terahertz (THz) pulses that are stable at high repetition rates and exhibit versatile and tailored properties.
Integration of Fields
MIMOSA relies on the integration of trans-disciplinary fields in:
- Bio-imaging
- Optics
- Ultrafast lasers and intense THz sources
- Big-data treatment
- Physics of the interaction between THz waves and matter
THz Source Development
MIMOSA aims to prototype in parallel an efficient intense THz source based on a new technology with ultrafast high-energy fiber lasers. This source can be used in nano-tomography for biological and medical applications but also as a test platform for a foreseeable commercialization of the THz-triggered TAP.
Team Expertise
The MIMOSA team members are leaders in:
- TAP development
- 3D medical and bio-imaging
- Ultrafast lasers development with advanced techniques for shaping and control of the optical beams properties
- Theoretical physics
With MIMOSA, we are uniquely positioned to succeed and to raise the competitiveness of Europe in microscopy development on the international scene.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 3.591.780 |
| Totale projectbegroting | € 3.591.780 |
Tijdlijn
| Startdatum | 1-9-2022 |
| Einddatum | 31-8-2026 |
| Subsidiejaar | 2022 |
Partners & Locaties
Projectpartners
- CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRSpenvoerder
- CONSIGLIO NAZIONALE DELLE RICERCHE
- ACTIVE FIBER SYSTEMS GMBH
- FONDAZIONE BRUNO KESSLER
- INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
- CHALMERS TEKNISKA HOGSKOLA AB
- INSTITUTUL NATIONAL DE CERCETAREDEZVOLTARE PENTRU MICROTEHNOLOGIE
- UNIVERSITE DE ROUEN NORMANDIE
- UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
- UNIVERSITA DEGLI STUDI DI TRENTO
- UNIVERSITE DE ROUEN NORMANDIE
- ECOLE DE TECHNOLOGIE SUPERIEURE
Land(en)
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