NONLINEAR DYNAMICS OF FLUCTUATING TWO-DIMENSIONAL MATERIALS IN ACTION
NCANTO aims to harness nonlinear dynamics in 2D materials to create highly-sensitive nanomechanical devices for improved frequency stability and single-cell sensing in drug development.
Projectdetails
Introduction
Two-dimensional (2D) materials are unique platforms for studying fundamental science. They bridge the gap between the world of atomic scale dynamics and the world of macroscopic mechanical vibrations. Owing to their small size, they can enable exploration of research areas that lie at the forefront of classical and quantum technologies.
Challenges
However, their noisy and nonlinear nature limits their performance. This combination of fluctuations and nonlinearities brings to light a new regime of mechanics that has remained largely untapped. If well understood, this regime can open a wide range of trajectories in high-performance sensing and lab-on-a-chip devices.
Project Goals
NCANTO aims at elucidating the strong interplay between nonlinearities and noise at the atomic scale. The project will leverage the acquired knowledge to engineer 2D nanomechanical devices that:
- Offer extreme frequency stability.
- Enable robust and highly-sensitive single-cell sensing.
Research Approach
To realize this vision, I will explore the influence of a range of nonlinear dynamic phenomena on two important noise sources, namely frequency fluctuations and biological noise. My approach will combine state-of-the-art modelling and experimental techniques to deliver novel designs that utilize nonlinear dynamic phenomena at their core.
Expected Outcomes
These designs will:
- Quench frequency noise in 2D resonators for breakthrough performance.
- Enhance biological rhythms at the single-cell level for robust drug screening.
By linking stochastic dynamics, nanomechanics, nonlinear dynamics, and structural optimization, I will develop a multidisciplinary research area that will enable a groundbreaking leap forward in the utilization of 2D materials as nonlinear sensors in frequency-based metrology and bio-health.
Conclusion
NCANTO will thus not only herald new frontiers in nanomechanics but will also open new routes towards engineering nanotools for rapid screening tests in drug development and personalized medicine.
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 1.999.021 |
Totale projectbegroting | € 1.999.021 |
Tijdlijn
Startdatum | 1-6-2024 |
Einddatum | 31-5-2029 |
Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- TECHNISCHE UNIVERSITEIT DELFTpenvoerder
Land(en)
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The Spectrum of Fluctuations in Living Matter
This project aims to develop a theoretical framework for predicting active fluctuations in living matter by analyzing subcellular and tissue-scale dynamics, enhancing our understanding of biological processes.
Efficient and functional optical frequency conversion in 3D Nonlinear Optical Artificial Materials
Developing 3D nano-engineered nonlinear optical materials to enhance frequency conversion efficiency and overcome limitations of bulk nonlinear crystals for advanced optical technologies.
Three Dimensional Quantum Nanomaterials
This project aims to explore the physics of 3D quantum nanomaterials through advanced experimental techniques, enhancing understanding and applications in technology and fundamental research.
Nanoprobes for Nonequilibrium Driven Systems
This project aims to develop fluorescent nanosensors to quantify energy dissipation in nonequilibrium biological systems, enhancing understanding of molecular motors and thermodynamic constraints.
Dynamic nanocluster – biomolecule interfaces
DYNANOINT aims to develop multiscale simulation strategies using graph theory and machine learning to enhance the understanding of metal nanoclusters for applications in bioimaging and nanomedicine.