MIRACLE the platform for virtual biopsies; introducing Metabolic MRI-as-a-Service for oncologic care

MIRACLE aims to develop a non-invasive MRI add-on for virtual biopsies, enabling personalized cancer treatment decisions by providing structural and metabolic tumor information globally.

Subsidie
€ 2.495.127
2022

Projectdetails

Introduction

Imagine a future where the limitless possibilities of virtual biopsies in cancer diagnostics can be explored. A future in which cancer patients would have access to MRI-enabled virtual biopsies in order to receive the best possible treatment decisions anywhere on the globe.

Project Overview

MIRACLE is developing a first-of-its-kind add-on device for MRI scanners that will be used to acquire a virtual biopsy of the tumor. This device will provide not only structural information on tumor dimensions for (tissue conserving) surgery but also unique metabolic information on the efficacy of specific systemic therapies.

Ultimately, this fully non-invasive, accurate, and rapid predictive approach can guide patients to the best fitting treatment plan given their personal circumstances and tumor characteristics.

Collaboration and Development

WaveTronica (WT), together with the University Medical Centre Utrecht (UMCU), German Cancer Research Centre (DKFZ), and Medical University of Lublin (UMLUB), aim to build this future by bringing the first Metabolic MRI-as-a-Service solution to the market.

Past projects and research led to the development of a Proof-of-Concept MRI coil capable of detecting metabolic biomarkers non-invasively using the strongest clinically available MRI system. This was demonstrated in:

  1. FET-OPEN-01-2016-2017-801075 - the Non-Invasive-Chemistry-Imaging (NICI)
  2. FET-OPEN-03-2018-2019-2020 - FET Innovation Launchpad - MIRACLE

The MRI coil is a plug-and-play add-on for existing MRI machines, resulting in an accessible and affordable virtual biopsy tool that can identify cancer biomarkers and tumor activity without shedding a drop of patient blood.

Service Transformation

This project converts a complex research tool into an accessible diagnostic service (Metabolic MRI-as-a-Service). MIRACLE is supported by the Dutch reimbursement company VGZ, Tesla DC, and oncologists, showing there is a strong market demand.

Next Steps

Now the challenge lies in bringing the breast coil PoC hardware and software to the next level using breast cancer as a use case.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 2.495.127
Totale projectbegroting€ 2.498.128

Tijdlijn

Startdatum1-5-2022
Einddatum30-4-2025
Subsidiejaar2022

Partners & Locaties

Projectpartners

  • WAVETRONICA BVpenvoerder
  • DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
  • UNIWERSYTET MEDYCZNY W LUBLINIE
  • UNIVERSITAIR MEDISCH CENTRUM UTRECHT

Land(en)

NetherlandsGermanyPoland

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