A Paradigm Shift in Health Monitoring with Electrospun Enzymatic Neomaterials

Introduction

Global healthcare associated with chronic non-healing wounds can be considered a main public health problem as it affects up to 2% of the world population. A novel approach is needed mainly to support the quality of life of the people suffering from this silent epidemic and additionally, alleviate the impact in costs and resources for the healthcare system.

Current State of Technology

Up to date, no smart bandages have made it to the real market and research state is still ongoing for a reliable and sensitive inspection method.

Project Goals

The main goal of the WOUNDSENS project is to lead the development of a novel generation of wearable biosensors with a synergy of technological breakthroughs in transversal fields of knowledge.

Key Innovations

1. Sensor elements will, for the first time, directly become a compatible part of the wound dressing material itself, resulting in enhanced wearing comfort and operability.
2. They will be integratable into manufacturers' existing standard processes (suturing, embroidery, roll-to-roll).

Technological Advancements

Our proposal presents a paradigm shift in smart wound dressings constructed on novel hollow fibers with radial bio-signaling based on engineered novel enzymes.

Leading-Edge Technologies

WOUNDSENS presents a leading-edge new technology with:

• The design and development of innovative electrochemical materials with step forward advances in conductive material.
• The development of electrospun neofibers and processes with leading-edge methodologies on electrospinning.
• The enzyme engineering of a new family of detection biocatalysts (resurrected and extant enzymes) to secure a sensitive and reliable signal.

Conclusion

WOUNDSENS proposal accepts the challenge of pushing forward the new technological platform to design a new concept in continuous wound control and monitoring, improving the life of millions of people.