SubsidieMeestersStrongly Enhanced Sensitivity EPR through Bimodal Resonators and Quantum-Limited Amplifiers
The Strong-ESPRESSO project aims to revolutionize EPR sensitivity using advanced resonators and amplifiers, enabling rapid analysis of complex spin systems like protein droplets and single cells.
Projectdetails
Introduction
Electron paramagnetic resonance (EPR) is a powerful tool employed across various disciplines including structural biology, chemistry, physics, material science, and many others. It provides important and unique information on a local electron spin environment, electronic properties, and dynamics of various paramagnetic centers.
Limitations of EPR
However, a relatively low sensitivity of this method often limits the range and type of systems that can be studied. Thus, major advancements in EPR sensitivity are crucial to significantly broaden its applicability, encompassing new and highly relevant systems such as single cells.
Project Overview
The Strongly Enhanced Sensitivity EPR through Bimodal Resonators and Quantum-Limited Amplifiers (Strong-ESPRESSO) project will ignite a revolution in EPR by employing sophisticated bimodal microwave resonators and intricate ways of noise reduction in tandem with novel microwave amplifiers developed for quantum technologies.
Objectives
We will achieve this by:
- Delivering a new generation of EPR cryoprobe heads, which will utilize the orthogonal-field bimodal cavities, allowing us to reach the sensitivity limit of these instruments.
- Transferring the bimodal cavity concept to planar superconducting microresonators, enabling the employment of these tools to study tiny (pL volume) samples of typical fast-decohering spin systems (e.g., protein droplets).
- Developing an ultra-sensitive EPR setup based on the radiative cooling effect of the bimodal resonators and recent advances in the quantum-limited microwave amplifiers.
Expected Impact
This revolutionary new setup is expected to provide a ground-breaking 5000x reduction in the EPR measurement time, simultaneously preserving compatibility with ordinary EPR experiments and samples.
Applications
Throughout the project, we will immediately apply the developed tools to study new and intricate spin systems in the fields of:
- Catalysis
- Protein droplets
- Single cells
This will lead to major impacts far beyond EPR.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.499.919 |
| Totale projectbegroting | € 2.499.919 |
Tijdlijn
| Startdatum | 1-4-2025 |
| Einddatum | 31-3-2030 |
| Subsidiejaar | 2025 |
Partners & Locaties
Projectpartners
- VILNIAUS UNIVERSITETASpenvoerder
Land(en)
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