SubsidieMeestersGamma-Neutron Vision aimed at improved cancer treatments in Hadron Therapy
This project aims to develop a portable device for simultaneous gamma-ray and thermal neutron imaging to enhance ion-range verification and secondary neutron dose assessment in proton therapy.
Projectdetails
Introduction
Proton therapy represents one of the most recent and advanced tools in cancer treatment, especially for complex cases and pediatric patients. Despite its exponential deployment worldwide, hadron therapy still faces two main limitations, which are related to:
- Accurate ion-range verification
- Assessment of the secondary (unwanted) neutron dose.
Project Overview
The present proposal presents an innovative tool that can help to improve this situation and thus increase the potential benefits of hadron therapy. This project focuses on a portable device that can simultaneously image both gamma-rays and thermal neutrons, which are ineluctably produced during the treatment.
Thermal Neutron Imaging
On one hand, imaging thermal neutrons may help to quantify more reliably the secondary neutron dose received by the patient during therapy.
Gamma-Ray Imaging
Complementary gamma-ray imaging is accomplished with the same apparatus by means of electronic collimation, thus enabling real-time assessment of the ion-range. In terms of gamma-vision, the system has been recently tested in pre-clinical conditions at CNA-Seville and HIT-Heidelberg.
Project Goals
This POC project aims therefore at demonstrating the additional neutron-vision capability, thereby elevating the full GNVision system to TRL6 and addressing its commercial viability in the health sector.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 150.000 |
| Totale projectbegroting | € 150.000 |
Tijdlijn
| Startdatum | 1-1-2024 |
| Einddatum | 31-12-2025 |
| Subsidiejaar | 2024 |
Partners & Locaties
Projectpartners
- AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICASpenvoerder
Land(en)
Vergelijkbare projecten binnen European Research Council
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Prompt Gamma Time Imaging: a new medical-imaging modality for adaptive Particle TherapyThe project aims to enhance particle therapy efficacy and safety by developing Prompt Gamma Time Imaging for real-time monitoring of treatment, improving dose control and adaptive dosimetry. | ERC Starting... | € 1.498.969 | 2022 | Details |
Advanced imaging system for Medical ApplicationsThe i-TED project aims to demonstrate the applicability of a gamma-ray imaging system in intraoperative Radio-Guided Surgery and neutron dose assessment in boron-neutron capture therapy. | ERC Proof of... | € 150.000 | 2023 | Details |
Portal Range Monitoring in Mixed Ion Beam SurgeryPROMISE aims to revolutionize carbon ion radiotherapy by developing mixed ion beams for real-time tumor monitoring, enhancing treatment precision and potentially improving patient outcomes. | ERC Consolid... | € 2.000.000 | 2024 | Details |
Targeted nanohorns for lithium neutron capture therapyTARLIT aims to enhance neutron capture therapy for cancer by using nanoparticles to deliver enriched lithium compounds, improving treatment precision and efficacy against tumors. | ERC Proof of... | € 150.000 | 2023 | Details |
Nanoscintillators to potentiate brain cancer radiotherapy: from physics to preclinical trialsThis project aims to enhance radiation therapy for glioblastoma by studying nanoscintillators' effects on tumor tissues, improving treatment efficacy while minimizing damage to healthy cells. | ERC Starting... | € 1.948.125 | 2024 | Details |
Prompt Gamma Time Imaging: a new medical-imaging modality for adaptive Particle Therapy
The project aims to enhance particle therapy efficacy and safety by developing Prompt Gamma Time Imaging for real-time monitoring of treatment, improving dose control and adaptive dosimetry.
Advanced imaging system for Medical Applications
The i-TED project aims to demonstrate the applicability of a gamma-ray imaging system in intraoperative Radio-Guided Surgery and neutron dose assessment in boron-neutron capture therapy.
Portal Range Monitoring in Mixed Ion Beam Surgery
PROMISE aims to revolutionize carbon ion radiotherapy by developing mixed ion beams for real-time tumor monitoring, enhancing treatment precision and potentially improving patient outcomes.
Targeted nanohorns for lithium neutron capture therapy
TARLIT aims to enhance neutron capture therapy for cancer by using nanoparticles to deliver enriched lithium compounds, improving treatment precision and efficacy against tumors.
Nanoscintillators to potentiate brain cancer radiotherapy: from physics to preclinical trials
This project aims to enhance radiation therapy for glioblastoma by studying nanoscintillators' effects on tumor tissues, improving treatment efficacy while minimizing damage to healthy cells.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Development of innovative proton and neutron therapies with high cancer specificity by 'hijacking' the intracellular chemistry of haem biosynthesis.NuCapCure aims to develop novel cancer treatments for glioblastoma by utilizing custom-made drugs through biosynthesis to enhance proton and neutron therapies for better targeting and efficacy. | EIC Pathfinder | € 5.972.875 | 2024 | Details |
NEXT GENERATION IMAGING FOR REAL-TIME DOSE VERIFICATION ENABLING ADAPTIVE PROTON THERAPYThe NOVO project aims to develop a groundbreaking real-time dose verification technology for proton radiotherapy, enhancing personalized cancer treatment and improving patient outcomes. | EIC Pathfinder | € 3.759.489 | 2024 | Details |
Treatment planning assessment for the Optiflux radiosurgery systemDit project ontwikkelt een innovatieve radiotherapie met sub-MeV X-stralen voor nauwkeurige tumorbehandeling en minder schade aan omliggende organen. | Mkb-innovati... | € 20.000 | 2021 | Details |
2D Material-Based Multiple Oncotherapy Against Metastatic Disease Using a Radically New Computed Tomography ApproachPERSEUS aims to develop a novel nanotechnology-based cancer therapy that activates under CT imaging to treat deep-seated, drug-resistant tumors with minimal side effects. | EIC Pathfinder | € 2.740.675 | 2023 | Details |
Radically New Cancer Therapy Based on Advances in Nanotechnology and Photonics for Simultaneous Imaging and Treatment of Solid TumoursScanNanoTreat aims to revolutionize cancer treatment by integrating advanced imaging and therapy technologies to improve patient outcomes and reduce costs, targeting clinical trials by 2027. | EIC Transition | € 2.499.911 | 2025 | Details |
Development of innovative proton and neutron therapies with high cancer specificity by 'hijacking' the intracellular chemistry of haem biosynthesis.
NuCapCure aims to develop novel cancer treatments for glioblastoma by utilizing custom-made drugs through biosynthesis to enhance proton and neutron therapies for better targeting and efficacy.
NEXT GENERATION IMAGING FOR REAL-TIME DOSE VERIFICATION ENABLING ADAPTIVE PROTON THERAPY
The NOVO project aims to develop a groundbreaking real-time dose verification technology for proton radiotherapy, enhancing personalized cancer treatment and improving patient outcomes.
Treatment planning assessment for the Optiflux radiosurgery system
Dit project ontwikkelt een innovatieve radiotherapie met sub-MeV X-stralen voor nauwkeurige tumorbehandeling en minder schade aan omliggende organen.
2D Material-Based Multiple Oncotherapy Against Metastatic Disease Using a Radically New Computed Tomography Approach
PERSEUS aims to develop a novel nanotechnology-based cancer therapy that activates under CT imaging to treat deep-seated, drug-resistant tumors with minimal side effects.
Radically New Cancer Therapy Based on Advances in Nanotechnology and Photonics for Simultaneous Imaging and Treatment of Solid Tumours
ScanNanoTreat aims to revolutionize cancer treatment by integrating advanced imaging and therapy technologies to improve patient outcomes and reduce costs, targeting clinical trials by 2027.