Hyperpolarized NMR made simple

Introduction

Nuclear magnetic resonance (NMR) is one of the most powerful analytical techniques currently available, with applications ranging from synthetic chemistry to clinical diagnosis. Despite the progress in developing new systems, applications are often limited by the low sensitivity of NMR.

Hyperpolarization Techniques

Hyperpolarization techniques have the potential to overcome this limitation and revolutionize the use of compact NMR. However, the state-of-the-art devices for hyperpolarization are limited by:

1. The need for cryogenic cooling
2. Long setup and polarization times with the risk of experimental failure
3. Costly systems
4. Cumbersome equipment
5. A limited range of polarizable molecules

MAGSENSE Project

The MAGSENSE project significantly simplifies the existing hyperpolarized NMR paradigm. Our unique approach is to produce spin order in standard hydrogen molecules to act as polarization batteries.

NMR Sample Analysis

The NMR sample with the enhanced target molecules is placed in a standard NMR spectrometer for ultrasensitive analysis. No modifications are required to the customer's existing NMR instrumentation. MAGSENSE provides significant advantages in:

• Signal enhancement
• Measurement times

This enables the analysis of intermediate steps in the chemical reaction.

Opportunities in Various Fields

MAGSENSE will provide many new opportunities for the fields of:

• Synthetic chemistry
• Analytical chemistry
• NMR research

It will be a market-creating innovation with point-of-service applications, such as diagnosis in ICU units.

Engagement and Support

The project will create opportunities for young researchers in the NMR field through our engagement with universities and technology institutes. At the same time, interested industry players have shown their support for the project.

NVision Team

NVision is backed by leading deep-tech VC funds from the US and Europe and currently employs more than 25 physicists, engineers, and material scientists, including professionals with more than 10 years of experience in NMR research, technology development, and project management.