Prostate cancer diagnostics using a non-invasive test based on innovative glycan-based scanning
ProSCAN aims to clinically validate a non-invasive liquid biopsy test for early-stage prostate cancer detection, potentially reducing unnecessary biopsies and associated costs significantly.
Projectdetails
Introduction
Prostate cancer (PCa) is the 2nd most frequent cancer in men with 1.4M new annual cases and nearly 0.4M deaths worldwide in 2020. PCa incidence is expected to increase to 2.1M cases and 0.6M annual deaths by 2035. Statistically, 1 in 8 men will get PCa in their lifetime.
Importance of Early Detection
However, nearly 50% of cancer deaths may be avoided if PCa were detected at early stages. Survival is proportional to the stage reached at the time of diagnosis - hence early-stage diagnostics is key to reduce mortality.
Project Aim
Our aim is to clinically validate and register ProSCAN, an affordable, non-invasive next-generation liquid biopsy PCa diagnostic test with a final accuracy of up to 90%.
Innovation in Diagnostics
The ProSCAN is the first test for early-stage PCa diagnostics based on glycan analysis in blood. ProSCAN will identify healthy men and those at risk of PCa, who need a confirmatory biopsy.
Impact on Healthcare
Being so accurate, ProSCAN will eliminate approximately 1.6M avoidable biopsies with the cost of around €1.5bn (in the EU and the US alone).
Financiële details & Tijdlijn
Financiële details
Subsidiebedrag | € 1.987.387 |
Totale projectbegroting | € 2.839.125 |
Tijdlijn
Startdatum | 1-10-2021 |
Einddatum | 29-2-2024 |
Subsidiejaar | 2021 |
Partners & Locaties
Projectpartners
- GLYCANOSTICS SROpenvoerder
Land(en)
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Prostate Diagnosis using Optical Coherence Tomography
The PROCT project aims to enhance prostate cancer diagnosis by developing a semiautonomous robotic system using Optical Coherence Tomography for accurate, in vivo lesion analysis without biopsies.
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PCaVision aims to enhance prostate cancer diagnosis using cost-effective ultrasound imaging and algorithms, improving patient access and reducing healthcare costs across 16 EU clinics.
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LASERBLOOD aims to develop a non-invasive blood test using fluorescence lifetime analysis of personalized protein corona to enable early detection of pancreatic cancer, potentially reducing mortality rates significantly.
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This project aims to develop a simple, portable, and cost-effective quantitative test for ovarian cancer biomarkers to enhance early detection and improve patient outcomes.
AI and Robotics for Prostate Biopsy
The ROBIOPSY project aims to develop a robotic prostate biopsy prototype for clinical trials, enhancing diagnostic accuracy and addressing health economics for improved cancer treatment.