Immune Photo-Activated Cancer Therapy for the Treatment of Upper Tract Urothelial Cancer (UTUC) and other solid tumours

Padeliporfin-VTP therapy offers a minimally invasive treatment for UTUC by using laser-activated photosensitizers to eliminate tumors while preserving organ function, aiming for regulatory approval and market entry.

Subsidie
€ 2.498.730
2024

Projectdetails

Introduction

UTUC is a non-systemically treatable cancer that forms in the renal pelvis or ureter, frequently recurring due to ineffective systemic chemotherapy. With 5-10% of urothelial cancers being UTUC, current surgical treatment solutions pose significant hardships on patients and decrease their quality of life.

Proposed Solution

Our proprietary solution, Padeliporfin-VTP therapy, offers a minimally invasive and effective alternative to surgery. This therapy delivers an inactive photosensitizer drug that is precisely activated in the tumour micro-environment by non-thermal laser light.

Mechanism of Action

  • Immediately impedes the tumour's blood supply
  • Leads to cell death with minimal effect on healthy tissues

Benefits of Treatment

This treatment not only effectively eliminates tumours but also preserves organ functionality for potential future treatments.

Project Leadership

This project is led by a team of accomplished professionals in the pharmaceutical and biopharma industry, which solidifies our capability in innovating best-in-class therapeutic solutions.

Funding and Market Goals

Utilising this funding, we aim to achieve:

  1. Regulatory approval (TRL9)
  2. Scale production
  3. Achieve market penetration in a market projected to reach €4.39B by 2032.

Financiële details & Tijdlijn

Financiële details

Subsidiebedrag€ 2.498.730
Totale projectbegroting€ 2.498.730

Tijdlijn

Startdatum1-12-2024
Einddatum30-11-2026
Subsidiejaar2024

Partners & Locaties

Projectpartners

  • IMPACT BIOTECH LTDpenvoerder

Land(en)

Israel

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