SubsidieMeestersExtracellular Vesicles Fiber Optic Surface Plasmon Resonance selection and analysis
FOX has developed an automated, label-free fiber-optic technology for rapid, precise purification and quantification of extracellular vesicles directly from crude samples, enhancing diagnostics and R&D.
Projectdetails
Introduction
The Extracellular vesicles (EV) field is growing due to increased interest in their roles in diagnostics and therapeutics. Current methods to purify and quantify EVs take a long time, introduce a bias, are costly, and imprecise, thereby hampering advancement in the EV R&D field.
Challenges in Current Methods
The lack of methods to quantify EVs directly in crude samples restricts applications in diagnostic and bioprocessing.
Breakthrough Technology
FOX has established a breakthrough label-free technology in a fiber-optic concept in an automated platform that allows biomolecular interaction research of biologicals.
FOx Affinity Isolation
The FOx affinity isolation and simultaneous quantification with a sensor dip probe is a new method that is:
- Selective (no bias)
- Automated (scalable 4x)
- Faster (time/24)
- Specific (purity >95%)
This method allows accurately quantifying EVs directly from crude samples.
Advantages of the New Method
Moreover, it allows for the first time to release the quantified and specifically selected EVs for further quantitative content analysis.
Financiële details & Tijdlijn
Financiële details
| Subsidiebedrag | € 2.499.999 |
| Totale projectbegroting | € 3.590.952 |
Tijdlijn
| Startdatum | 1-7-2023 |
| Einddatum | 30-6-2025 |
| Subsidiejaar | 2023 |
Partners & Locaties
Projectpartners
- FOX BIOSYSTEMS NVpenvoerder
Land(en)
Vergelijkbare projecten binnen EIC Accelerator
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
TowArd demoCRatization Of ev-BAsed TherapiesEVerZom aims to revolutionize EV manufacturing with a patented scalable process, targeting GMP compliance and commercial production to lead the European market in clinical applications. | EIC Accelerator | € 1.700.000 | 2022 | Details |
TowArd demoCRatization Of ev-BAsed Therapies
EVerZom aims to revolutionize EV manufacturing with a patented scalable process, targeting GMP compliance and commercial production to lead the European market in clinical applications.
Vergelijkbare projecten uit andere regelingen
| Project | Regeling | Bedrag | Jaar | Actie |
|---|---|---|---|---|
Geintegreerd systeem voor fractionering karakterisatie en kwantificatie van extracellulaire blaasjes en hun inhoudCelnext Biotechnologies onderzoekt de haalbaarheid van een geïntegreerd microfluidisch systeem met optische biosensoren voor gestandaardiseerde isolatie en analyse van extracellulaire blaasjes (EBs). | Mkb-innovati... | € 20.000 | 2021 | Details |
automated in-line separatioN and dEtection of eXtracellular vesicles for liqUid biopsy applicationSThe NEXUS project aims to industrialize a customizable platform for the separation and analysis of extracellular vesicles from biofluids, enhancing cancer diagnostics and monitoring. | EIC Transition | € 2.497.750 | 2022 | Details |
Reliable and scalable procedures for the isolation and loading of extracellular vesiclesLABORIOUS aims to develop innovative methods for isolating and loading therapeutic agents into exosomes, enhancing their clinical application in various diseases while minimizing membrane damage. | ERC Proof of... | € 150.000 | 2024 | Details |
High-Throughput Production of Extracellular Vesicles from Organoids under Rotating MotionThe project aims to develop a streamlined system for high-throughput production of extracellular vesicles (EVs) by integrating controlled cell configurations to enhance therapeutic potential. | ERC Proof of... | € 150.000 | 2024 | Details |
Versatile Amplification Method for Single-Molecule Detection in Liquid BiopsyVerSiLiB aims to develop an enzyme-free amplification platform for detecting proteins and nucleic acids in liquid biopsies, enhancing cancer management through novel affinity-mediated transport. | EIC Pathfinder | € 2.994.244 | 2022 | Details |
Geintegreerd systeem voor fractionering karakterisatie en kwantificatie van extracellulaire blaasjes en hun inhoud
Celnext Biotechnologies onderzoekt de haalbaarheid van een geïntegreerd microfluidisch systeem met optische biosensoren voor gestandaardiseerde isolatie en analyse van extracellulaire blaasjes (EBs).
automated in-line separatioN and dEtection of eXtracellular vesicles for liqUid biopsy applicationS
The NEXUS project aims to industrialize a customizable platform for the separation and analysis of extracellular vesicles from biofluids, enhancing cancer diagnostics and monitoring.
Reliable and scalable procedures for the isolation and loading of extracellular vesicles
LABORIOUS aims to develop innovative methods for isolating and loading therapeutic agents into exosomes, enhancing their clinical application in various diseases while minimizing membrane damage.
High-Throughput Production of Extracellular Vesicles from Organoids under Rotating Motion
The project aims to develop a streamlined system for high-throughput production of extracellular vesicles (EVs) by integrating controlled cell configurations to enhance therapeutic potential.
Versatile Amplification Method for Single-Molecule Detection in Liquid Biopsy
VerSiLiB aims to develop an enzyme-free amplification platform for detecting proteins and nucleic acids in liquid biopsies, enhancing cancer management through novel affinity-mediated transport.